*Often affects older animals but kittens of 16 weeks old and puppies of 20 weeks old have been reported.
*Often affects older animals but kittens of 16 weeks old and puppies of 20 weeks old have been reported.
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==Description==
==Description==
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'''Lymphocytic - plasmacytic enteritis (LPE)''' is the most common form of [[Inflammatory Bowel Disease|Inflammatory Bowel Disease]] (IBD). As its name suggests, the predominant cell type in the intestinal mucosa is [[Lymphocytes|'''lymphocytes''']] and '''plasma cells'''. Enteric parasites, bacteria in dogs and [[Toxoplasma|''Toxoplasma'']] in cats have been reported to associated with LPE. This disorder in cats have also been shown to associate with concurrent disease of the pancreas and liver such as [[Pancreatitis - Dog and Cat|pancreatitis]], [[Cholangitis|cholangitis]] and [[Hepatic Lipidosis|hepatic lipidosis]]. LPE is believed to be caused by an abnormal [[Regional Lymphoid Tissue - Anatomy & Physiology|mucosal associated lymphoid tissue (MALT)]] response to luminal bacterial, dietary or self-antigens.
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'''Lymphocytic - plasmacytic enteritis (LPE)''' is the most common form of [[Inflammatory Bowel Disease|Inflammatory Bowel Disease]] (IBD). As its name suggests, the predominant cell type in the intestinal mucosa is [[Lymphocytes - Introduction|'''lymphocytes''']] and '''plasma cells'''. Enteric parasites, bacteria in dogs and [[Toxoplasma gondii|''Toxoplasma'']] in cats have been reported to associated with LPE. This disorder in cats have also been shown to associate with concurrent disease of the pancreas and liver such as [[Pancreatitis|pancreatitis]], [[Cholangitis|cholangitis]] and [[Hepatic Lipidosis|hepatic lipidosis]]. LPE is believed to be caused by an abnormal [[Regional Lymphoid Tissue - Anatomy & Physiology|mucosal associated lymphoid tissue (MALT)]] response to luminal bacterial, dietary or self-antigens.
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The [[Small Intestine - Anatomy & Physiology|small intestines]] are affected to a variable degree of severity. It has also been known to affect other parts of the gastrointestinal tract such as the [[:Category:Stomach and Abomasum - Pathology|stomach]] and the [[Colon - Anatomy & Physiology|colon]]. In severely affected animals, this will result in a protein-losing enteropathy (PLE).
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The [[Small Intestine Overview - Anatomy & Physiology|small intestines]] are affected to a variable degree of severity. It has also been known to affect other parts of the gastrointestinal tract such as the [[:Category:Stomach and Abomasum - Pathology|stomach]] and the [[Colon - Anatomy & Physiology|colon]]. In severely affected animals, this will result in a protein-losing enteropathy (PLE).
==Diagnosis==
==Diagnosis==
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*** Changes in the relative and absolute numbers of plasma cells and lymphocytes have been associated with IBD in humans.
*** Changes in the relative and absolute numbers of plasma cells and lymphocytes have been associated with IBD in humans.