Cats are particularly susceptible to development of severe cobalamin deficiency and hence should be supplemented every two weeks to maintain normal serum cobalamin levels. Long term monitoring of serum cobalamin is advised. Similarly cats with EPI may also have subnormal Vitamin E levels which should be measured and corrected. A Vitamin K responsive coagulopathy has been reported in cats and hence it is sensible to examine the vitamin K status of cats with EPI.
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In cats Cobalamin absorption depends on adequate secretion of intrinsic factor, in cats 99% of intrinsic factor is released from the exocrine pancreas and subsequently cats with EPI are frequently cobalamin deficient. Cats diagnosed with EPI should be supplemented every two weeks to maintain normal serum cobalamin levels. Long term monitoring of serum cobalamin is advised. Similarly cats with EPI may also have subnormal Vitamin E levels which should be measured and corrected. A Vitamin K responsive coagulopathy has been reported in cats and hence it is sensible to examine the vitamin K status of cats with EPI.