Changes

==Description==

==Description==

[[Exocrine Pancreatic Insufficiency| Exocrine Pancreatic Insufficiency]] is a rare disease in cats but can occur following [[Pancreatitis, Chronic Interstitial|chronic pancreatitis]].  

[[Exocrine Pancreatic Insufficiency| Exocrine Pancreatic Insufficiency]] is a rare disease in cats but can occur following [[Pancreatitis, Chronic Interstitial|chronic pancreatitis]].  

==Diagnosis==

==Diagnosis==

===History===

===History===

===Clinical signs===

===Clinical signs===

Weight loss and muscle wastage are usually seen in assosiation with EPI. Diarrhoea and steatorrhoea are also common. Cats may present with a wet, greasy looking body coat particularly around the perineal area, this may be a result of fatty soiling or secondary to cobalamin deficiency. Cats with EPI may also have concurrent Diabetes mellitus.   

Weight loss and muscle wastage are usually seen in assosiation with EPI. Diarrhoea and steatorrhoea are also common. Cats may present with a wet, greasy looking body coat particularly around the perineal area, this may be a result of fatty soiling or secondary to cobalamin deficiency.   

===Laboratory Tests===

===Laboratory Tests===

Serum concentrations of cobalamin are often decreased. Serum folate concentrations may also be decreased due to concurrent [[Inflammatory Bowel Disease|Inflammatory bowel disease]] or Intestinal lymphoma.

Serum concentrations of cobalamin are often decreased. Serum folate concentrations may also be decreased due to concurrent [[Inflammatory Bowel Disease|Inflammatory bowel disease]] or Intestinal lymphoma.

The most sensitive and specific test for the diagnosis of feline EPI is the feline trypsin-like immunoreactivity assay('''fTLI'''). The values are greatly reduced as compared to normal animals. Values '''<8µg/l''' in cats are considered diagnostic. This test must be carried out after withdrawing food for several hours. Unfortunatley the fTLI assay is only available from specialist laboratories, other tests are available but are often inconvenient and expensive.

The most sensitive and specific test for the diagnosis of feline EPI is the feline trypsin-like immunoreactivity assay('''fTLI'''). The values are greatly reduced as compared to normal animals. Values '''<8µg/l''' in cats are considered diagnostic. This test must be carried out after withdrawing food for several hours. Unfortunatley the fTLI assay is only available from specialist laboratories, other tests are available but are often inconvenient and expensive.

 

===Other===

===Other===

Atrophy of the pancreas seen via exploratory laparotomy or laparoscopy

Atrophy of the pancreas seen via exploratory laparotomy or laparoscopy