Changes

Equine Protozoal Myeloencephalitis (view source)

Revision as of 17:37, 8 July 2010

725 bytes added , 17:37, 8 July 2010

→‎Pathology

Line 32: Line 32:

====Biopsy====

====Pathology====

+

Lesions: There is focal discoloration, hemorrhage, and/or malacia of CNS tissue. Histologically, protozoa are found in association with a mixed inflammatory cellular response and neuronal destruction. Schizonts, in various stages of maturation, or free merozoites commonly are seen in the cytoplasm of neurons or mononuclear phagocytes. Also parasitized are intravascular and tissue neutrophils and eosinophils and, more rarely, capillary endothelial cells and myelinated axons. Merozoites may be found extracellularly, especially in areas of necrosis. In at least 75% of cases, protozoa are not seen on H&E-stained sections, and the diagnosis is made on the basis of characteristic focal or multifocal inflammatory change.

+

====Treatment====

Treatment and Control:

Nmr28

1,406

edits