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| [[Image:Dipylidium caninum 2.jpg|right|150px|thumb|''Dipylidium caninum'' - Courtesy of the Laboratory of Parasitology, University of Pennsylvania School of Veterinary Medicine]] | | [[Image:Dipylidium caninum 2.jpg|right|150px|thumb|''Dipylidium caninum'' - Courtesy of the Laboratory of Parasitology, University of Pennsylvania School of Veterinary Medicine]] |
| ==Overview== | | ==Overview== |
− | Cyclophyllidae cestodes have an indirect life cycle involving one or more intermediate hosts before developing into adult form in the definitive host. Eggs must be ingested by an intermediate host species, once ingested the gastric and intestinal secretions breakdown the thick shell and activate the 6-hooked oncosphere. The oncosphere uses its hooks to tear through the gastrointestinal mucosa to reach the blood or lymph system. In invertebrate hosts the oncosphere will enter directly into the body cavity from the gastrointestinal tract. The oncosphere then travels to its predeliction site, loses its hooks and develops into the larval stage known as a metacestode. This can be one of a number of forms dependant on the species of cestode. | + | Cyclophyllidae cestodes have an indirect life cycle involving one or more intermediate hosts before developing into adult form in the definitive host. Eggs must be ingested by an intermediate host species, once ingested the gastric and intestinal secretions breakdown the thick shell and activate the 6-hooked oncosphere. The oncosphere uses its hooks to tear through the gastrointestinal mucosa to reach the blood or lymph system. In invertebrate hosts the oncosphere will enter directly into the body cavity from the gastrointestinal tract. The oncosphere then travels to its predeliction site, loses its hooks and develops into the larval stage known as a metacestode. This can be one of a number of forms dependant on the species of cestode. When the metacestode is ingested by the final host, the scolex attaches to the gastrointestinal mucosa, the remainder of the structure is digested, and a chain of proglottids (segments) begins to grow from the base of the scolex. Eggs are produced within the terminal proglottid of the chain which is shed into the feaces of the host once the production is complete. |
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| + | Infection of the final-host involves at least three epidemiological relationships: |
| + | 1) '''predator-prey''', e.g. cat eating infected mouse |
| + | 2) '''accidental''', e.g. horse eating infected pasture mites |
| + | 3) '''irritation''', e.g. infected flea on animal = exaggerated grooming of animal = swallowed |
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| ==Metacestodes== | | ==Metacestodes== |
| There are six types of metacestode (in increasing order of complexity: | | There are six types of metacestode (in increasing order of complexity: |
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| ===Hydatid cyst=== | | ===Hydatid cyst=== |
| + | This metacestode consists of a fluid filled bladder that can grow to a considerable size. It is lined by a germinal epithilium that buds off to form brood capusules. These brood capsules contain multible inverted scolices and are termed '''hydatid sand'''. The response from the host is to wall off the cyst with fibrous tissue around the germinal layer. |
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− | 5) '''Hydatid cyst''': the metacestode of Echinococcus granulosus; this fluid-filled bladder can grow to the size of a football; it is lined with germinal epithelium that buds off brood capsules internally; inverted scolices form inside these; hydatid sand is the name given to the brood capsules and scolices in the hydatid fluid; the host attempts to wall off the hydatid cyst with fibrous tissue; between this and the germinal membrane is an amorphous layer
| + | ===Alveolar cyst=== |
− | | + | Similar to the hydatid cyst however the alveolar cyst forms daughter cysts, these bud off from the internal and external surface of the germinal layer. These pubs enable the cyst to invade into the tissue of the organ rather like a tumor. |
− | 6) '''Alveolar cyst''': the metacestode of Echinococcus multilocularis; this is like the hydatid cyst, but daughter cysts bud off the external, as well as the internal, surface of the germinal layer, with the result that the metacestode expands by infiltrating through the tissue, rather like a tumour.
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− | When the metacestode is ingested by the final host, the scolex attaches to the mucosa, the remainder of the structure is digested, and a chain of proglottids (segments) begins to grow from the base of the scolex.
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− | Infection of the final-host involves at least three epidemiological relationships:
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− | 1) '''predator-prey''', e.g. cat eating infected mouse
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− | 2) '''accidental''', e.g. horse eating infected pasture mites
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− | 3) '''irritation''', e.g. infected flea on animal = exaggerated grooming of animal = swallowed
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− | [[Category:Cyclophyllidea]][[Category:To_Do_-_NickJ]] | + | [[Category:Cyclophyllidea]] |
| + | [[Category:To_Do_-_NickJ]] |