Changes

==Treatment==

==Treatment==

A long course (4-6 weeks), of an appropriate antibiotic should be given in light of bacterial culture and sensitivity results. Selected antibiotic should be excreted in the bile in active form, and should be active against aerobic and anaerobic intestinal coliforms.[[Penicillins|Amoxicillin]] potentiated with clavulanic acid is a good initial choice. [[Nitroimidazoles|Metronidazole]] may be added to extend the spectrum of anaerobes and coliforms.

A long course (4-6 weeks), of an appropriate antibiotic should be given in light of bacterial culture and sensitivity results. Selected antibiotic should be excreted in the bile in active form, and should be active against aerobic and anaerobic intestinal coliforms. [[Penicillins|Amoxicillin]] potentiated with clavulanic acid is a good initial choice. [[Nitroimidazoles|Metronidazole]] may be added to extend the spectrum of anaerobes and coliforms.

Surgery is warranted if discrete choleliths or complete biliary obstruction is identified. In cases of complete extrahepatic biliary obstruction, surgical decompression and cholecystoduodenostomy or cholecystojejunostomy should be performed.

Surgery is warranted if discrete choleliths or complete biliary obstruction is identified. In cases of complete extrahepatic biliary obstruction, surgical decompression and cholecystoduodenostomy or cholecystojejunostomy should be performed.

[[Liver Drugs|Ursodeoxycholic acid]] may be given as it has hepatoprotective (anti-inflammatory, immunomodulatory and antifibrotic effects) properties and choleretic effect.  The latter promotes increased fluidity of biliary secretions for treating or preventing sludging.

[[Liver Drugs|Ursodeoxycholic acid]] may be given as it has hepatoprotective (anti-inflammatory, immunomodulatory and antifibrotic effects) properties and choleretic effect.  The latter promotes increased fluidity of biliary secretions for treating or preventing sludging.

Aggressive supportive care is required due to severe illness. Fluid and electrolyte derangements should be corrected and Vitamin K1 may be given if bleeding diatheses develop. A high protein diet rather than a protein-restricted diet is more appropriate for feeding anorexic cats to prevent the development of [[Hepatic Lipidosis|hepatic lipidosis]]

Aggressive supportive care is required due to severe illness. Fluid and electrolyte derangements should be corrected and Vitamin K1 may be given if bleeding diatheses develop. A high protein diet rather than a protein-restricted diet is more appropriate for feeding anorexic cats to prevent the development of [[Hepatic Lipidosis|hepatic lipidosis]]

Monitor response to treatment with serial complete haematology and biochemistry.

Monitor response to treatment with serial complete haematology and biochemistry.

==Prognosis==

==Prognosis==