Changes

==Pathology==

==Pathology==

Post mortem examination often shows the liver to be enlarged and pale with rounded edges. Generalised icterus is often present. Histologically there may signs of acute be centrilobular to midzonal necrosis with mononuclear cell accumulation within the portal triads. Contusions, lacerations or fractures may be present if the disease has had a violent clinical course.  

Post mortem examination often shows the liver to be enlarged and pale with rounded edges. Generalised icterus is often present. Histologically there may signs of acute hepatocellular degeneration. be centrilobular to midzonal necrosis with mononuclear cell accumulation within the portal triads. Contusions, lacerations or fractures may be present if the disease has had a violent clinical course.