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| Blood urea coentration may be elevated independently of creatinine for the following reasons: | | Blood urea coentration may be elevated independently of creatinine for the following reasons: |
| *Gastro-intestinal haemorrhage, as with [[Gastric Ulceration - Dog|gastro-duodenal ulceration]]. | | *Gastro-intestinal haemorrhage, as with [[Gastric Ulceration - Dog|gastro-duodenal ulceration]]. |
− | *Diet with high purine content, such as liver. | + | *Diet with high protein or purine content, such as liver. |
| + | *Increased catabolism of body tissues, particularly muscle, which may occur in pyrexic animals or those with systemic disease. |
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− | Reduced urea concentration: | + | Reduced urea concentration may occur due to: |
| + | *Over-enthusiastic fluid therapy, diluting the urea present in the blood. |
| + | *Disease that cause polyuria and/or polydipsia may cause 'medullary washout' of urea. Common examples include pyschogenic polydipsia, [[Diabetes Insipidus|diabetes insipidus]] and [[Canine Hyperadrenocorticism - Cushing's Disease|Cushing's disease]]. |
| + | *Reduced synthesis with [[Portosystemic Shunt|porto-systemic shunts]], [[Hepatic Microvascular Dysplasia|microvascular dysplasia]] or liver failure. |
| + | *A diet with a low protein content or malnutrition. |
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| [[Category:Blood_Sample]][[Category:Dog]][[Category:Cat]][[Category:Cattle]][[Category:Sheep]][[Category:Horse]][[Category:Pig]][[Category:Donkey]][[Category:To_Do_-_James]] | | [[Category:Blood_Sample]][[Category:Dog]][[Category:Cat]][[Category:Cattle]][[Category:Sheep]][[Category:Horse]][[Category:Pig]][[Category:Donkey]][[Category:To_Do_-_James]] |