Changes

FIP should be suspected in all cases of chronic weight loss or recurrent fever unresponsive to antibiotics, particularly in multiple cat situations.

FIP should be suspected in all cases of chronic weight loss or recurrent fever unresponsive to antibiotics, particularly in multiple cat situations.

Simple serology is impossible as most cats will have antibody to FECoV

Simple serology is impossible as most cats will have antibody to FECoV

However, 4 indicators can be used to cross reference:

However, 4 indicators can be used to cross reference:

**High FECoV Ab titres

*High FECoV Ab titres

**Low albumin:globulin ratio in plasma/ascites (globulin levels rise in FIP)

*Low albumin:globulin ratio in plasma/ascites (globulin levels rise in FIP)

**High levels of glycoprotein alpha 1-acid glycoprotein (AGP)

*High levels of glycoprotein alpha 1-acid glycoprotein (AGP)

**Low white cell counts

*Low white cell counts

FIP antigen detection by '''immunofluorescence''' in macrophages gives a definite positive diagnosis

FIP antigen detection by '''immunofluorescence''' in macrophages gives a definite positive diagnosis