Changes

==Description==

==Description==

Feline eosinophilic granuloma complex includes three types of lesions:

Feline eosinophilic granuloma complex includes three types of lesions:

1)Eosinophilic ulcer which present as a well circumscribed, erythematous ulcer on the lip or oral mucosa of middle-aged cats. 2)Eosinophilic plaques which present as raised erythematous lesions on the skin of the medial thighs and abdomen. or 3)Eosinophilic granuloma which present on the posterior aspect of the rear legs of young cats and also found on the tongue, palate and oral mucosa.

1)Eosinophilic ulcer which present as a well circumscribed, erythematous ulcer on the lip or oral mucosa of middle-aged cats 2)Eosinophilic plaques which present as raised erythematous lesions on the skin of the medial thighs and abdomen 3)Eosinophilic granuloma which present on the posterior aspect of the rear legs of young cats and also found on the tongue, palate and oral mucosa.

Eosinophilic granulomas of the oral cavity appear as yellow/pink raised linear lesions. They can occur on the oral mucosa, hard palate mucosa, soft palate, or the base of the tongue. Cats with eosinophilic lesions of the mouth often have concurrent skin lesions.  

Eosinophilic granulomas of the oral cavity appear as yellow/pink raised linear lesions. They can occur on the oral mucosa, hard palate mucosa, soft palate, or the base of the tongue. Cats with eosinophilic lesions of the mouth often have concurrent skin lesions.  

==Treatment==

==Treatment==

Initial medical treatment is to control any ectoparasites. Secondly a diet trial and skin testing may be carried out to rule out food allergy and atopy. If there is evidence of a bacterial infection [[Antibiotics|antibiotics]].

Initial medical treatment is to control any ectoparasites. Secondly a diet trial and skin testing may be carried out to rule out food allergy and atopy. If there is evidence of a bacterial infection [[Antibiotics|antibiotics]] are necessary.

If the patient is refractory to the above [[Steroids|Corticosteroid]] should be administered. Treatment should be tapered gradually once a response is seen then discontinued once signs have completely disappeared.

If the patient is refractory to the above [[Steroids|Corticosteroid]] should be administered. Treatment should be tapered gradually once a response is seen then discontinued once signs have completely disappeared.

Chlorambucil may also be useful in resistent cases.

Chlorambucil may also be useful in resistent cases.

==Prognosis==

==Prognosis==

Good but the lesion can recur.

Good but the lesion can recur.

==References==

==References==

*Tutt, C., Deeprose, J. and Crossley, D. (2007) '''BSAVA Manual of Canine and Feline Dentistry (3rd Edition)''' ''BSAVA''

Tutt, C., Deeprose, J. and Crossley, D. (2007) '''BSAVA Manual of Canine and Feline Dentistry (3rd Edition)''' ''BSAVA''

*Nelson, R.W. and Couto, C.G. (2009) '''Small Animal Internal Medicine (Fourth Edition)''' ''Mosby Elsevier''

Nelson, R.W. and Couto, C.G. (2009) '''Small Animal Internal Medicine (Fourth Edition)''' ''Mosby Elsevier''

==From Pathology==

==From Pathology==

 

====Pathogenesis====

==Pathology==

*Histologically lots of eosinophils, polymorphs.  

*Histologically lots of eosinophils, polymorphs.  

*Exaggerated eosinophilic response.

*Exaggerated eosinophilic response.