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===Pathology===
===Pathology===
Findings at post mortem depend on the route of entry of the organism, whether it became generalised or not and the stage of the disease.
One or more lymph nodes will display the chacteristic granulomatous tubercules. In the respiratory form the mediastinal and bronchial lymph nodes are affected, with lesions in the lungs.
If the mycobacteria disseminated from the primary complex then lymph nodes in other regions will also be affected and there will be multiple small foci of infection on other organs.
==Treatment==
==Treatment==
Treatment is not usually an option due to the chronic nature of the disease, zoonotic potential and test and slaughter policy.
Treatment is not usually an option due to the chronic nature of the disease, zoonotic potential and test and slaughter policy.
The mycobacterium reside within macrophages in the lungs where they multiply and result in characteristic [[Lungs Inflammatory - Pathology#Granulomatous pneumonia|granulomatous inflammation]] The regional lymph nodes and also affected
**90% of cases exhibit the pulmonary form
**90% of cases exhibit the pulmonary form
**Grossly:
**Grossly:
***Ulcers in [[Trachea Inflammatory - Pathology|trachea]] and [[Bronchi and Bronchioles Inflammatory - Pathology#Infectious causes of bronchitis or bronchiolitis|bronchi]] due to coughed up bacteria
***Ulcers in [[Trachea Inflammatory - Pathology|trachea]] and [[Bronchi and Bronchioles Inflammatory - Pathology#Infectious causes of bronchitis or bronchiolitis|bronchi]] due to coughed up bacteria
***Spreads into [[Pleural Cavity & Membranes Inflammatory - Pathology|pleura]]
***Spreads into [[Pleural Cavity & Membranes Inflammatory - Pathology|pleura]]
**Microscopically:
**Microscopically:
***Epitheliod and giant cells at centre of tubercles
***Epitheliod and giant cells at centre of tubercles
****Macrophages with ingested bacteria, forming epithelioid cells - large vesicular nuclei, abundant pale cytoplasm
****Macrophages with ingested bacteria, forming epithelioid cells - large vesicular nuclei, abundant pale cytoplasm
*some tubercle bacilli enter the lymph and travel to the bronchial or mediastinal nodes
*some tubercle bacilli enter the lymph and travel to the bronchial or mediastinal nodes
*inhaled bacilli reach the alveoli, set up a focus of inflammation
*inhaled bacilli reach the alveoli, set up a focus of inflammation
::- leads to type IV (delayedd type) hypesensitivity
::- leads to type IV (delayedd type) hypesensitivity
::- 'caseous' or cheesy type of necrosis
::- 'caseous' or cheesy type of necrosis
=====Tuberculosis pleurisy=====
=====Tuberculosis pleurisy=====