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==Description==

==Description==

Feline eosinophilic granuloma complex includes three types of lesions:

Feline eosinophilic granuloma complex includes three types of lesions:

1)Eosinophilic ulcer which present as a well circumscribed, erythematous ulcer on the lip or oral mucosa of middle-aged cats 2)Eosinophilic plaques which present as raised erythematous lesions on the skin of the medial thighs and abdomen 3)Eosinophilic granuloma which present on the posterior aspect of the rear legs of young cats and also found on the [[Tongue - Anatomy & Physiology|tongue]], [[Hard Palate - Anatomy & Physiology|hard palate]] and oral mucosa.

# Eosinophilic ulcer which present as a well circumscribed, erythematous ulcer on the lip or oral mucosa of middle-aged cats  

# Eosinophilic plaques which present as raised erythematous lesions on the skin of the medial thighs and abdomen  

# Eosinophilic granuloma which present on the posterior aspect of the rear legs of young cats and also found on the [[Tongue - Anatomy & Physiology|tongue]], [[Hard Palate - Anatomy & Physiology|hard palate]] and oral mucosa.

Eosinophilic granulomas of the oral cavity appear as yellow/pink raised linear lesions. They can also occur on the soft palate, or the base of the tongue. Cats with eosinophilic lesions of the mouth often have concurrent skin lesions.  

Eosinophilic granulomas of the '''oral cavity''' appear as '''yellow/pink raised linear lesions'''. They can also occur on the soft palate, or the base of the tongue. Cats with eosinophilic lesions of the mouth often have concurrent skin lesions.  

The cause of feline eosinophilic granuloma is unknown but it has been associated with food and insect bite allergies, atopy, immunosuppression, bacteral and viral infections.

The cause of feline eosinophilic granuloma is unknown but it has been associated with food and insect bite allergies, atopy, immunosuppression, bacteral and viral infections.

==Signalment==

==Signalment==

More commonly found in young cats (2-6 years) and also more common in females than males.

More commonly found in young cats (2-6 years) and also more common in females than males.

   

   

==Diagnosis==

==Diagnosis==

==Clinical Signs==

==Clinical Signs==

Depending on site of lesion can include dysphagia,halitosis and anorexia.

Depending on site of lesion can include dysphagia,halitosis and anorexia.

==Laboratory tests==

==Laboratory tests==

A peripheral blood [[Eosinophilia|eosinophilia]] may be present.

A peripheral blood [[Eosinophilia|eosinophilia]] may be present.

==Pathology==

==Pathology==

Histologically lots of eosinophils and polymorphs are present. There is also an exaggerated eosinophilic response.

A deep biopsy specimen of the mass is required for a definitive diagnosis.  Histology reveals an eosinophilic tissue infiltrate and polymorphs are present. There is also an exaggerated eosinophilic response.

==Treatment==

==Treatment==

Initial medical treatment is to control any ectoparasites. Secondly a diet trial and skin testing may be carried out to rule out food allergy and atopy. If there is evidence of a bacterial infection [[Antibiotics|antibiotics]] are necessary.

Initial medical treatment is to control any ectoparasites. Secondly a diet trial and skin testing may be carried out to rule out food allergy and atopy. If there is evidence of a bacterial infection [[Antibiotics|antibiotics]] are necessary.

If the patient is refractory to the above [[Steroids|Corticosteroid]] should be administered. Treatment should be tapered gradually once a response is seen then discontinued once signs have completely disappeared.

If the patient is refractory to the above [[Steroids|Corticosteroid]] should be administered. Treatment should be tapered gradually once a response is seen then discontinued once signs have completely disappeared.

   

   

Surgical excision is required for large lesions that interfere with breathing or swallowing.

Surgical excision is required for large lesions that interfere with breathing or swallowing.

[[Category:To_Do_-_Caz]]

[[Category:To_Do_-_Caz]]

[[Category:To_Do_-_Review]]

[[Category:Expert_Review]]