Changes

==Pathogenesis==

==Pathogenesis==

MAP is primarily spread through herds via faecal-oral transmission, contaminated water, in utero and through infected milk and colostrum.

MAP is primarily spread through herds via faecal-oral transmission, contaminated water, in utero and through infected milk and colostrum. Following ingestion of M. paratuberculosis, infection begins in the ileum. Following uptake by the Peyer's Patches, M. paratuberculosis infects macrophages in the gastrointestinal tract and lymph nodes.

There are '''three''' stages of infection in Johne's disease.

There are '''three''' stages of infection in Johne's disease.