See [[Colic, Medical Treatment|Medical Treatment of Colic in Horses]].
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*Initially intermittent abdominal pain controlled with analgesics:
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**Flunixin meglumine 0.25-1.1mg/kg IV every 6-12 hours
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**Butorphanol 0.05-0.1 mg/kg IV every 6-8 hours
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**Xylazine 0.3-0.5mg/kg IV as needed
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*Oral laxatives to soften the impaction:
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**Liquid paraffin or mineral oil 2-4lites by nasogastric tube every 12 to 24 hours
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**Anionic surfactant dioctyl sodium succinate (DSS) 6-12g/500kg diluted in 2-4litres of water by nasogastric tube every 12-24 hours
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*Saline cathartics such as magnesium sulphate 0.1 mg/kg in 2-4litres by nasgastric tube may also be useful
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*Prevent access to feed
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Aggressive oral and IV fluid therapy (2-4 times maintenance) if impactions persist(83)
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===Surgical===
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If impaction remains unresolved, pain becomes uncontrollable, or extensive gas distension of the colon occurs, surgery is indicated. Abodominocentesis can be used to monitor the onset of intestinal compromise.(83) At surgery the contents of the colon are evacuated via a pelvic flexure enterotomy.