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==Gross Pathology==
 
==Gross Pathology==
The infected host appears emaciated. Fat is pale and oedematous, and only present in small amounts. 
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Lesions are usually localised to the terminal portion of the ileum.  The mucosal surface is diffusely thickened with transverse, corrugated rugae which do not disappear when the intestinal wall is stretched. In sheep and goats however, nodule formation with necrosis and calcification may be seen.
Signs are confined to the terminal [[Small Intestine - Anatomy & Physiology|small intestine]] (especially the [[Ileum - Anatomy & Physiology|ileum]]) but are characteristic.  The mucosal surface is diffusely thickened with transverse, corrugated rugae. Infected animals may also have enlarged mesenteric lymph nodes.
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Infected animals may also have enlarged mesenteric lymph nodes.
    
[[Image:johnes disease proliferative ileitis.jpg|thumb|right|150px|Proliferative ileitis in Johnes disease (Courtesy of Bristol BioMed Image Archive)]]
 
[[Image:johnes disease proliferative ileitis.jpg|thumb|right|150px|Proliferative ileitis in Johnes disease (Courtesy of Bristol BioMed Image Archive)]]
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[[Category:Enteritis,_Granulomatous]]
 
[[Category:Enteritis,_Granulomatous]]
 
[[Category:To_Do_-_SophieIgnarski]]
 
[[Category:To_Do_-_SophieIgnarski]]
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