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The main common neurological disorder of rabbits is head tilt or torticollis.
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The main common neurological disorder of rabbits is head tilt or torticollis; there are several causes.
There are several causes
      
==Aetiology==
 
==Aetiology==
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These include the bacteria listed above as causing peripheral vestibular disease (with the addition of ''Listeria monocytogenes'')and also protozoan diseases (eg. ''Encephalitozoon cuniculi'' and ''Toxoplasma gondii''). ''Encephalitozoon'' is not found in the inner ear tissue, only in the CNS where it causes a non-suppurative meningitis and a granulomatous encephalitis, sometimes accompanied by perivascular infiltration with lymphocytes and plasma cells. All areas of the brain are affected.
 
These include the bacteria listed above as causing peripheral vestibular disease (with the addition of ''Listeria monocytogenes'')and also protozoan diseases (eg. ''Encephalitozoon cuniculi'' and ''Toxoplasma gondii''). ''Encephalitozoon'' is not found in the inner ear tissue, only in the CNS where it causes a non-suppurative meningitis and a granulomatous encephalitis, sometimes accompanied by perivascular infiltration with lymphocytes and plasma cells. All areas of the brain are affected.
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E cuniculi may yield biochemical test results indicative of renal disorder and positive serology for E cuniculi antibodies. Note E cuniculi also causes ophthalmic lesions (capsular rupture, cataract development and phacoclastic [[Uveitis – Rabbit|uveitis]]).  
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''E. cuniculi'' may yield biochemical test results indicative of renal disorder and positive serology for ''E. cuniculi'' antibodies. Note that ''E. cuniculi'' also causes ophthalmic lesions (capsular rupture, cataract development and phacoclastic [[Uveitis – Rabbit|uveitis]]).  
    
Treatment of ''E. cuniculi'' is described [[Encephalitozoon cuniculi – Rabbit|here]]. For treatment of toxoplasmosis consider sulphonamides and be aware that clindamycin is extremely toxic in this species.
 
Treatment of ''E. cuniculi'' is described [[Encephalitozoon cuniculi – Rabbit|here]]. For treatment of toxoplasmosis consider sulphonamides and be aware that clindamycin is extremely toxic in this species.
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*Consider absorption from topical applications
 
*Consider absorption from topical applications
 
*Compromisation of premunity  
 
*Compromisation of premunity  
*In anorexia, mobilizes free fatty acids from adipose tissue =>hepatic lipidosis
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*In anorexia, mobilizes free fatty acids from adipose tissue => hepatic lipidosis
 
*Increased populations of intestinal coliforms
 
*Increased populations of intestinal coliforms
 
*Ratio of aerobes to anaerobes alters
 
*Ratio of aerobes to anaerobes alters
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'''Note: Chronic pruritic seborroeic otitis is usually associated with yeasts (''Candida'' sp.) whereas purulent otitis, especially where the discharge is tacky and sticky, may show ''E. coli'' and ''Pseudomonas'' sp on culture.'''
 
'''Note: Chronic pruritic seborroeic otitis is usually associated with yeasts (''Candida'' sp.) whereas purulent otitis, especially where the discharge is tacky and sticky, may show ''E. coli'' and ''Pseudomonas'' sp on culture.'''
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==References==
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*Hillyer, E. V. (1994)  Pet Rabbits. Veterinary Clinics of North America: Small Animal Practice. 24 (1) 25-65. 
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*Keeble, E. (2006) Nervous and Musculoskeletal Disorders in BSAVA Manual of Rabbit Medicine and Surgery eds Meredith A and Flecknell P,  2nd Edition 2006, published by BSAVA Quedgley Glocs
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*Richardson, V.  (2000) Rabbits: Health, husbandry and disease. Blackwell Science, Oxford
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*Saunders, R. (2002) Understanding Head Tilt in Rabbits "New Directions": Small Animal Eyes and Ears (from the publishers of Veterinary Times) Issue 1, Volume 1, Feb 2002 pages 4-5
    
[[Category:Neurological_Disorders_-_Rabbit]]
 
[[Category:Neurological_Disorders_-_Rabbit]]
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