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Created page with "*Synonym: feline allergic bronchitis *Pathology very similar to COPD/SPA-RAO in horses and human asthma, although few published papers relating to it *Allergens - house dust mite..."
*Synonym: feline allergic bronchitis
*Pathology very similar to COPD/SPA-RAO in horses and human asthma, although few published papers relating to it
*Allergens - house dust mites, fungal spores
*Widespread narrowing of airways
**'''Extrinsic asthma'''
***Type I hypersensitivity in response to allergen challenge - mediated by [[IgE]]
***Pathological changes:
****Exudate into airways - mucus/ cells
****Thickened airway walls - oedema, glandular and smooth muscle hypertrophy, vascular congestion
****Altered fluidity of mucus (associated with goblet cell hyperplasia) -> less effective mucociliary apparatus
**'''Intrinsic asthma'''
***A proportion of cats there is an increased propensity for the bronchial smooth muscle to contract (increased bronchial reactivity) -> airway constriction
[[Category:Allergic Respiratory Diseases]][[Category:Cat]][[Category:To Do - Blood]]
*Pathology very similar to COPD/SPA-RAO in horses and human asthma, although few published papers relating to it
*Allergens - house dust mites, fungal spores
*Widespread narrowing of airways
**'''Extrinsic asthma'''
***Type I hypersensitivity in response to allergen challenge - mediated by [[IgE]]
***Pathological changes:
****Exudate into airways - mucus/ cells
****Thickened airway walls - oedema, glandular and smooth muscle hypertrophy, vascular congestion
****Altered fluidity of mucus (associated with goblet cell hyperplasia) -> less effective mucociliary apparatus
**'''Intrinsic asthma'''
***A proportion of cats there is an increased propensity for the bronchial smooth muscle to contract (increased bronchial reactivity) -> airway constriction
[[Category:Allergic Respiratory Diseases]][[Category:Cat]][[Category:To Do - Blood]]