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| + | ==[[Antibody Mediated Autoimmune Diseases]]== |
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− | ==Antibody mediated autoimmune diseases==
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− | [[Image:ImageNeeded.png|right|thumb|150px|Myasthenia gravis]]
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− | ===1. Immune Mediated Haemolytic Anaemia (IMHA)===
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− | '''Pathogenesis:''' [[Type II Hypersensitivity - WikiBlood|Type II hypersensitivity]]
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− | * Autoantibody attack on the red blood cells causing extravascular and intravascular lysis which causes anaemia.
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− | * The in saline autoagglutination test and the coombes test is used to diagnose the disorder.
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− | ===2. Immune Mediated Thrombocytopaenia (IMTP) ===
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− | '''Pathogenesis:''' [[Type II Hypersensitivity - WikiBlood|Type II hypersensitivity]]
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− | * There is an immunological attack on the platelets which reduces the ability for clotting.
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− | * A reduced platelet count and detection of anti-platelet antibodies in the serum are used for diagnosis of this disorder.
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− | ===3. Myasthenia gravis===
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− | '''Pathogenesis:''' [[Type II Hypersensitivity - WikiBlood|Type II hypersensitivity]]
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− | ===4. Bullous Pemphigoid===
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− | '''Pathogenesis:''' [[Type II Hypersensitivity - WikiBlood|Type II hypersensitivity]]
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− | ===5. Pemphigus Vulgaris===
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− | '''Pathogenesis:''' [[Type II Hypersensitivity - WikiBlood|Type II hypersensitivity]]
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− | ===6. Systemic Lupus Erythematosus (SLE)/Multi-systemic immune mediated disease===
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− | '''Pathogenesis:''' [[Type III Hypersensitivity - WikiBlood|Type III hypersensitivity]]
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| ==Cell mediated autoimmune diseases== | | ==Cell mediated autoimmune diseases== |