Author, Donkey, Bureaucrats, Administrators
53,803
edits
Changes
Canine Cyclic Haematopoiesis (view source)
Revision as of 13:46, 12 August 2010
, 13:46, 12 August 2010Created page with "thumb|right|150px|Appearance of a puppy with Grey Collie syndrome - Copyright Michelle Tennis & Peggy Melton *Also called '''Grey Collie Syndro..."
[[Image:Grey Collie Syndrome.jpg|thumb|right|150px|Appearance of a puppy with Grey Collie syndrome - Copyright Michelle Tennis & Peggy Melton]]
*Also called '''Grey Collie Syndrome'''
*Autosomal recessive
*Insertion mutation in AP3B1 gene
*Diluted grey coat colour, stunted growth, poor wound healing
*Neutropenia every 2 weeks which lasts 3-4 days due to cyclic production of cells from [[Bone Marrow - Anatomy & Physiology|bone marrow]]
*Animals are prone to recurrent infections, mainly from the respiratory and gastrointestinal tract
**E.g. pyrexia, [[Diarrhoea|diarrhoea]], gingivitis and arthritis
*Puppies can be distinguished from other litter mates by the diluted grey colouring
*Affected puppies show symptoms such as fever, joint pain and eye, skin and respiratory infections from 8 weeks of age
*Affected animals rarely live beyond 2-3 years with most puppies dying within a few weeks of birth
[[
*Also called '''Grey Collie Syndrome'''
*Autosomal recessive
*Insertion mutation in AP3B1 gene
*Diluted grey coat colour, stunted growth, poor wound healing
*Neutropenia every 2 weeks which lasts 3-4 days due to cyclic production of cells from [[Bone Marrow - Anatomy & Physiology|bone marrow]]
*Animals are prone to recurrent infections, mainly from the respiratory and gastrointestinal tract
**E.g. pyrexia, [[Diarrhoea|diarrhoea]], gingivitis and arthritis
*Puppies can be distinguished from other litter mates by the diluted grey colouring
*Affected puppies show symptoms such as fever, joint pain and eye, skin and respiratory infections from 8 weeks of age
*Affected animals rarely live beyond 2-3 years with most puppies dying within a few weeks of birth
[[