Changes

**'''Splenic contraction''' pushes sequestered platelets into the circulation.  This phenomenon is especially marked in horses which have a muscular splenic capsule.   

**'''Splenic contraction''' pushes sequestered platelets into the circulation.  This phenomenon is especially marked in horses which have a muscular splenic capsule.   

**'''Splenectomy''' prevents the sequestration of platelets in the spleen, resulting in constantly increased levels of platelets.

**'''Splenectomy''' prevents the sequestration of platelets in the spleen, resulting in constantly increased levels of platelets.

**As part of a response to '''[[Anaemia – Introduction|anaemia]]''', a '''reactive thrombocytosis''' is often documented and this may precede signs of regeneration.

**As part of a response to '''[[Anaemia - Introduction|anaemia]]''', a '''reactive thrombocytosis''' is often documented and this may precede signs of regeneration.

*Pathological

*Pathological

**'''Essential thrombocythaemia''' is a rare myeloproliferative disease that results in the excessive production of platelets which function abnormally.  Affected animals suffer from bouts of spontaneous haemorrhage.

**'''Essential thrombocythaemia''' is a rare myeloproliferative disease that results in the excessive production of platelets which function abnormally.  Affected animals suffer from bouts of spontaneous haemorrhage.