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Interventional Agents (view source)
Revision as of 18:11, 8 September 2010
, 18:11, 8 September 2010→Phenylephrine
==Phenylephrine==
==Phenylephrine==
Phenylephrine is an α adrenergic sympathomimetic used to treat hypotension without cardiac stimulation. Due to metabolism in the gastrointestinal tract, it is available in an injectable form. It acts by causing peripheral vasoconstriction leading to an increase in blood pressure, both systolic and diastolic. However, a reflex bradycardia may be seen. There is a increase in coronary blood flow.
Phenylephrine is an α adrenergic sympathomimetic used to treat hypotension without cardiac stimulation. Due to metabolism in the gastrointestinal tract, it is available in an injectable form. It acts by causing peripheral vasoconstriction leading to an increase in blood pressure, both systolic and diastolic. However, a reflex bradycardia may be seen. There is a increase in coronary blood flow.
It is used to treat hypotension caused by a number of factors including barbituate anaesthesia, and has diagnostic opthlamic uses also. If administered intravenously onset is almost immediate, and duration of action is approximately 20 minutes, while if administered intramuscularly onset of action is approximately 10-15 minutes with a duration of action approximately 1 hour.
It is used to treat hypotension caused by a number of factors including barbituate anaesthesia, and has diagnostic opthlamic uses also. If administered intravenously onset is almost immediate, and duration of action is approximately 20 minutes, while if administered intramuscularly onset of action is approximately 10-15 minutes with a duration of action approximately 1 hour.
===Contraindications===
===Contraindications===