Changes

*Targets the [[Cardiorespiratory System Overview - Anatomy & Physiology|respiratory system]]

*Targets the [[Cardiorespiratory System Overview - Anatomy & Physiology|respiratory system]]

**Including the [[Paranasal sinuses - Anatomy & Physiology|paranasal sinuses]]

**Including the [[Paranasal Sinuses - Anatomy & Physiology|paranasal sinuses]]

**Also can be systemic, cutaneous, visceral, skeletal or ocular

**Also can be systemic, cutaneous, visceral, skeletal or ocular

*Affects the [[Nervous and Special Senses - Anatomy & Physiology#Central Nervous System (CNS)|CNS]] of dogs and cats

*Affects the [[Nervous and Special Senses - Anatomy & Physiology#Central Nervous System (CNS)|CNS]] of dogs and cats

**[[Paranasal sinuses - Anatomy & Physiology|paranasal sinuses]] and [[Pharynx - Anatomy & Physiology|pharynx]] can be infected with dissemination to the [[Nervous and Special Senses - Anatomy & Physiology#Central Nervous System (CNS)|CNS]] and other tissues

**[[Paranasal Sinuses - Anatomy & Physiology|paranasal sinuses]] and [[Pharynx - Anatomy & Physiology|pharynx]] can be infected with dissemination to the [[Nervous and Special Senses - Anatomy & Physiology#Central Nervous System (CNS)|CNS]] and other tissues

***E.g. [[Lungs - Anatomy & Physiology|Lungs]], [[Urinary System - Anatomy & Physiology#The Kidney|kidneys]] and [[Joints - Anatomy & Physiology|joints]]

***E.g. [[Lungs - Anatomy & Physiology|Lungs]], [[Urinary System - Anatomy & Physiology#The Kidney|kidneys]] and [[Joints - Anatomy & Physiology|joints]]

**Also causes subcutaneous granulomas

**Also causes subcutaneous granulomas