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*[[The_Ovary_-_Oogenesis_-_Anatomy_%26_Physiology|Oocyte]] surrounded by two or more layers of follicular cuboidal cells. These cells differentiate into the inner Granulosa cells and outer Theca cells.
 
*[[The_Ovary_-_Oogenesis_-_Anatomy_%26_Physiology|Oocyte]] surrounded by two or more layers of follicular cuboidal cells. These cells differentiate into the inner Granulosa cells and outer Theca cells.
 
* Connective tissue cells surrounding the granulosa cells differentiate to form the layers of theca cells which produce androgens.
 
* Connective tissue cells surrounding the granulosa cells differentiate to form the layers of theca cells which produce androgens.
* Theca cells produce Androstienedione which is converted to [[Endocrine_System_-_Ovaries_-_Anatomy_%26_Physiology|17β-Oestrodiol ]](E2) by the Granulosa cell enzyme Aromatase.
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* Theca cells produce Androstienedione which is converted to [[Ovaries_Endocrine_Function_-_Anatomy_%26_Physiology|17β-Oestrodiol ]](E2) by the Granulosa cell enzyme Aromatase.
*Granulosa cells become responsive to Follicle Stimulating Hormone (FSH) and start producing [[Endocrine_System_-_Ovaries_-_Anatomy_%26_Physiology|17β-Oestrodiol]] and small amounts of Inhibin and Progesterone.
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*Granulosa cells become responsive to Follicle Stimulating Hormone (FSH) and start producing [[Ovaries_Endocrine_Function_-_Anatomy_%26_Physiology|17β-Oestrodiol]] and small amounts of Inhibin and Progesterone.
 
* Despite the presence of the zona pellucida, the inner granulosa cells are able to communicate with the [[The_Ovary_-_Oogenesis_-_Anatomy_%26_Physiology|oocyte]] through gap junctions.
 
* Despite the presence of the zona pellucida, the inner granulosa cells are able to communicate with the [[The_Ovary_-_Oogenesis_-_Anatomy_%26_Physiology|oocyte]] through gap junctions.
 
* Following formation of the theca cells, the primary [[The_Ovary_-_Oogenesis_-_Anatomy_%26_Physiology|oocyte]] reaches full size.
 
* Following formation of the theca cells, the primary [[The_Ovary_-_Oogenesis_-_Anatomy_%26_Physiology|oocyte]] reaches full size.
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