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* The [[Hypothalamus_-_Anatomy_%26_Physiology|hypothalamus]] is inherently female.
 
* The [[Hypothalamus_-_Anatomy_%26_Physiology|hypothalamus]] is inherently female.
* [[Endocrine_System_-_Testes_-_Anatomy_%26_Physiology|Testosterone]] 'defeminizes' the brain during embryogenesis and eliminates the GnRH surge centre in males.
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* [[Testes Endocrine Function_-_Anatomy_%26_Physiology|Testosterone]] 'defeminizes' the brain during embryogenesis and eliminates the GnRH surge centre in males.
* The female foetus has no testes to produce [[Endocrine_System_-_Testes_-_Anatomy_%26_Physiology|testosterone]], thus developes a [[Hypothalamus_-_Anatomy_%26_Physiology|hypothalamic]] GnRH surge centre.
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* The female foetus has no testes to produce [[Testes Endocrine Function_-_Anatomy_%26_Physiology|testosterone]], thus developes a [[Hypothalamus_-_Anatomy_%26_Physiology|hypothalamic]] GnRH surge centre.
    
== Defeminizing the Hypothalamus in the Male ==
 
== Defeminizing the Hypothalamus in the Male ==
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* As a result, LH does not surge, it maintains a relatively consistent episodic pattern of secretion every day.
 
* As a result, LH does not surge, it maintains a relatively consistent episodic pattern of secretion every day.
 
** Episodes occur every 2-6 hours in the postpubertal male.
 
** Episodes occur every 2-6 hours in the postpubertal male.
* Steady, pulsatile GnRH and LH release results in a steady, pulsatile release of [[Endocrine_System_-_Testes_-_Anatomy_%26_Physiology|testosterone]].
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* Steady, pulsatile GnRH and LH release results in a steady, pulsatile release of [[Testes Endocrine Function_-_Anatomy_%26_Physiology|testosterone]].
    
== The Female Hypothalamus ==
 
== The Female Hypothalamus ==
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