Changes

There are several ways that vascular fragility may arise. Capillaries can be damaged by toxins - this occurs in severe bacterial infections in all species. [[:Category:Streptococcus species|Streptococcus]], [[:Category:Pasteurella and Mannheimia species|Pasteurella]] and [[Bacillus species|anthrax]] infections would be good examples of organisms that feature capillary damage as a symtom of infection.

There are several ways that vascular fragility may arise. Capillaries can be damaged by toxins - this occurs in severe bacterial infections in all species. [[:Category:Streptococcus species|Streptococcus]], [[:Category:Pasteurella and Mannheimia species|Pasteurella]] and [[Bacillus species|anthrax]] infections would be good examples of organisms that feature capillary damage as a symtom of infection.

Drug-induced damage to the vascular system does occur, although the mechanisms of damage induced by drugs are not clearly understood. Examples include heavy metals, e.g. lead, bismuth, mercury, iodides, fluorides, chlorinated hydrocarbon pesticides and salicylates.

Drug-induced and heavy metal damage to the vascular system does occur, although the mechanisms are not clearly understood. Examples include lead, bismuth, mercury, iodides, fluorides, chlorinated hydrocarbon pesticides and salicylates.

Vascular fragility can occur as a consequence of an underlying disease state, which is seen in allergy or anaphylactic reactions, connective tissue diseases such as Ehlers-Danlos syndrome in dogs, [[DM|Diabetes mellitus]] and antibody-antigen complex reactions.

Vascular fragility can occur as a consequence of an underlying disease state, which is seen in allergy or anaphylactic reactions, connective tissue diseases such as Ehlers-Danlos syndrome in dogs, [[DM|Diabetes mellitus]] and antibody-antigen complex reactions.