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An eosinophilic infiltrate may indicate a diet-induced, type 1 hypersensitivity.  However, most dogs do not respond to a purely exclusion diet.  Endoparasitism should also be excluded prior to immunosuppressive therapy for EE.
 
An eosinophilic infiltrate may indicate a diet-induced, type 1 hypersensitivity.  However, most dogs do not respond to a purely exclusion diet.  Endoparasitism should also be excluded prior to immunosuppressive therapy for EE.
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==Signalment==
===Focal===
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Focal EE is a disease of young dogs, which can be associated with [[Toxocara canis|''Toxocara canis'']] infection. Pin-head sized white nodules can be seen under the serosa in the bowel.
 
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* A disease of young dogs.
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* Associated with [[Toxocara canis|''Toxocara canis'']] infection.
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** Pin-head sized white nodules can be seen under the serosa in the bowel.
   
*** Consist of of eosinophils and occasionally macrophages and plasma cells.
 
*** Consist of of eosinophils and occasionally macrophages and plasma cells.
 
*** Can sometimes see [[Toxocara canis|''Toxocara'']] larvae in the nodules.
 
*** Can sometimes see [[Toxocara canis|''Toxocara'']] larvae in the nodules.
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*** Eosinophils heavily infiltrate all layers of stomach and intestines.
 
*** Eosinophils heavily infiltrate all layers of stomach and intestines.
 
**It has been suggested that it is a type of hypersensitivity reaction.
 
**It has been suggested that it is a type of hypersensitivity reaction.
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==Signalment==
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Focal EE is a disease of young dogs, which can be associated with [[Toxocara canis|''Toxocara canis'']] infection. Pin-head sized white nodules can be seen under the serosa in the bowel.
  −
*** Consist of of eosinophils and occasionally macrophages and plasma cells.
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*** Can sometimes see [[Toxocara canis|''Toxocara'']] larvae in the nodules.
      
This condition is seen in any breed or age, but is more common in younger animals and certain breeds:
 
This condition is seen in any breed or age, but is more common in younger animals and certain breeds:
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