Changes

Bronchoscopy may reveal increased amounts of mucous in the airways which may have a greenish appearance.  Tracheobronchial washes may show evidence of eosinophillic inflammation. Pulmonary specimens shouldbe carefully examined for the presence of infectious agents and for features of malignancy which may represent potential antigenic sources. Diagnosis may be complicated by the presence of a bacterial secondary infection resultng in a neutrophillic inflammation and a positiove culture on tracheal wash. Once the bacterial infection has been controlled, a second tracheobronchial wash may harvest eosinophils.   

Bronchoscopy may reveal increased amounts of mucous in the airways which may have a greenish appearance.  Tracheobronchial washes may show evidence of eosinophillic inflammation. Pulmonary specimens shouldbe carefully examined for the presence of infectious agents and for features of malignancy which may represent potential antigenic sources. Diagnosis may be complicated by the presence of a bacterial secondary infection resultng in a neutrophillic inflammation and a positiove culture on tracheal wash. Once the bacterial infection has been controlled, a second tracheobronchial wash may harvest eosinophils.   

==Treatment==

==Treatment==

Any underlying disease needs to be treated directly. Eliminating the source of the antigen that may the triggering the excessive immune response may result in a cure. The most effective management consists of ''corticosteroids''. When PIE is secondary to heartworm disease or pulmonary parasites, treatment with prednisolone before or during treatment antihelmintic treatment controls the pulmonary signs. Prolonged therapy is often needed when the underlying alergen is unknown starting at a high dose and gradually tapering down. When severe bronchoconstriction is suspected, ''bronchodilators'' or ''b2-agonists'' may be helpful.

Any underlying disease needs to be treated directly. Eliminating the source of the antigen that may the triggering the excessive immune response may result in a cure. The most effective management consists of ''corticosteroids''. When PIE is secondary to heartworm disease or pulmonary parasites, treatment with prednisolone before or during treatment antihelmintic treatment controls the pulmonary signs. Prolonged therapy is often needed when the underlying allergen is unknown starting at a high dose and gradually tapering down. When severe bronchoconstriction is suspected, ''bronchodilators'' or ''b2-agonists'' may be helpful.

<br> ''Eosinophilic Pulmonary Granulomatosis'' requires treatment with corticosteroids and a cytotoxic agent such as cyclophasphamide.  

<br> ''Eosinophilic Pulmonary Granulomatosis'' requires treatment with corticosteroids and a cytotoxic agent such as ''cyclophasphamide''.

==Prognosis==

==Prognosis==