• The hypoglossal nerve, CN XII provides motor innervation to the tongue.
  • Normally, a horse resists the tongue being retracted from the mouth.
    • The horse will quickly return the tongue after it is pulled out to the side.
  • Horses with hypoglossal weakness appear differently.
    • The tongue may protrude from the mouth.
    • Chronic unilateral hypoglossal lesions may result in unilateral tongue atrophy.
    • Bilateral hypoglossal lesions may result in difficulty prehending food.
  • Horses with cerebral dysfunction may have signs corresponding to tongue weakness.
    • However, tongue atrophy is not present in these animals.