Blue Eye Disease Flashcards

Question	Answer		Article
What causes Blue eye disease in pigs?	Blue-eye paramyxovirus (BEP) - a negative sense single stranded RNA (ssRNA) virus.		Link to Article
What viruses are closely related to it?	Mumps virus Simian virus 5		Link to Article
What are the properties of this virus?	Mainly spherical but it is polymorphic Enveloped - which is covered in surface projections 135-148nm by 257-360nm buoyant density in sucrose gradients of 1.21 g/ml. Six structural proteins and the envelope nucleocapsid expresses hemagglutinin-neuraminidase and fusion and matrix proteins. Resistant to actinomycin D and sensitive to chloroform, formalin and beta propiolactone.		Link to Article
What systems are affected by Blue eye disease?	Nervous systems Reproductive systems Respiratory systems		Link to Article
What clinical signs are associated with sows?	Domestic hosts include: Dogs Cats Pigs Wild hosts include: Rabbits Rats Ferral cats and dogs Peccary's Clinical signs are only seen in the pig, but antibodies can be detected in rabbits, rats, dogs and cats.		Link to Article
What ages of pigs are affected by this disease?	All: Piglets Weaners Growers Sows Boars		Link to Article
What clinical signs are generally associated with Blue eye disease in all ages of pigs?	Anorexia Weight loss Reluctance to move Dehydration Periorbital and conjunctival swelling (chemosis) Purulent/serous ocular discharge Corneal opacity. Neurological signs (tetraparesis, opisthotonus, dysmetria, proprioceptive disorders, tremors, nystagmus mydriasis, blindness, decreased or absent menace response) Respiratory signs (tachypnea, dyspnea, and open mouthed breathing)		Link to Article
	In the first third of gestation: Infertility Reproductive failures Embryonic mortality Return to oestrus In late gestation: Stillbirths Small litters Mummification		Link to Article
What clinical signs are associated with piglets and weaners?	Piglet and weaners: Prostration Hind limb stiffness Generalised weakness Muscle fasciculation’s Retarded growth Depression Excitation Head pressing Circling Hyperaesthesia Abnormal behaviour/aggression Coma In piglets: Changes in hair coat (dull/rough) Ocular erosions Enlarged distended bladder Constipation/reduction in faces or diarrhoea		Link to Article
What clinical signs are associated with boars?	Male infertility Lack of libido Haemospermia Orchitis with epidydimitis Swelling of the genitalia		Link to Article
What is the epidemiology of Blue eye disease?	The virus is spread via direct contact, fomites and possibly birds Virus can be found in the axon of neurons Original site of replication is thought to be the nasal mucosa and tonsils It can be found in tissues (lung, liver, spleen, kidney, lymph node, heart and testis) Hematogenous spread likely		Link to Article
What is the distribution of Blue eye disease in pigs?	The disease is economically important to Central Mexico and its states.		Link to Article

Further links

Blue-Eye Paramyxovirus Flashcards

Blue-Eye Paramyxovirus