Type II Hypersensitivity
Revision as of 13:50, 26 August 2008 by Mmadment (talk | contribs) (New page: right|thumb|150px|Type II Hypersensitivity-Brian Catchpole RVC 2008 Production of IgM or IgG to cell surface antigens or extracellular matrix protein...)
Production of IgM or IgG to cell surface antigens or extracellular matrix proteins.
"Neutralisation" blockade of receptors:
- Myasthenia gravis
Immunological attack on target cells, destroying them by:
1. Antibody dependent cell cytotoxicity (ADCC)
- Pemphigus vulgaris
- Bullous pemphigoid
2. Complement mediated lysis
- Self RBC antigen:
- Immune mediated haemolytic anaemia
- Foreign RBC:
- Blood transfusion reaction
- Haemolytic disease of new born (Rhesus disease in humans and neonatal isoerythrolysis in foals and kittens)
- RBC parasite:
- Feline infectious anaemia (Mycoplasma haemofelis)
3. Phagocytosis