Gut Development - Anatomy & Physiology

BACK TO DEVELOPMENTAL BIOLOGY

Introduction

The endoderm will form the lining of the gut and the organs that develop from it. Splanchnic mesoderm surrounds the endoderm and orginates from the lateral plate mesoderm. It will form the smooth muscle of the gut that are used for peristalsis.

Endoderm Development

1. At the anterior of the embryo, the endoderm invaginates.
   • This invagination is called the Anterior Intestinal Portal (AIP).
2. The ends of the endoderm are brought together by this invagination, which fuse together to close the endoderm.
3. A similar process occurs at the posterior of the embryo, an invagination occurs called the Caudal Intestinal Portal (CIP).
   • This closes the endoderm at the posterior of the embryo.
4. The invagination and closure spread to the middle of the anterior - posterior axis where they meet at the yolk stalk.
5. After the yolk has been metabolised, the yolk stalk can be closed.