Immunoglobulins Flashcards

IMMUNOGLOBULINS WIKIBLOOD FLASHCARDS

Immunoglobulins Structure and Function

Question	Answer	Article
What are immunoglobulins also known as?	Antibodies	Link to Answer Article
How many domains does the heavy chain have?	1 variable domain 3 or 4 constant domains	Link to Answer Article
How many domains does the light chain have?	1 variable domain 1 constant domain	Link to Answer Article
What are hypervariable domains?	Folded pockets of the variable domain into which antibody can bind Different antibodies have different amino acid sequences within the three variable domains	Link to Answer Article
What does Fab stand for and from which chain is it generated?	Fragment associated with antigen binding Light chain	Link to Answer Article
What does Fc stand for and from which chain is it generated?	Constant fragment Heavy chain	Link to Answer Article
What does the Fc fragment do?	Mediates phagocytosis Triggers inflammation Targets Ig to certain tissues	Link to Answer Article
What are the four major effects of antibodies?	Blockage and agglutination Promotion of phagocytosis Degranulation of mast cells/eosinophils Complement Fixation	Link to Answer Article

Immunoglobulins Classes

Question	Answer	Article
What are immunoglobulins also known as?	Antibodies	Link to Answer Article

Immunoglobulins Variation

Question	Answer	Article
What are immunoglobulins also known as?	Antibodies	Link to Answer Article

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