Host Invasion by Microorganisms Flashcards

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Host invasion

Question Answer Article
By what three routes can pathogens enter the body?
  • Contact
  • Aerosol
  • Orofecal
Link to Answer Article


Viruses

Question Answer Article
Naked viruses contain only...?
  • RNA/DNA and protein coat
Link to Answer Article
Name three functions of viral structural proteins
  • Protection of the genome
  • Attachment to host cell
  • Fusion of envelope to host cell membrane
Link to Answer Article
Name the two main innate defences against viral infection
  • Interferon
  • Natural killer cells
Link to Answer Article
Upon viral infection, which antibody isotype is increased at mucosal surfaces?
  • IgA
Link to Answer Article
What do antibodies stop free virus particles from doing?
  • Binding to host cell, entering and uncoating
Link to Answer Article
By what mechanism is complement able to damage the virion envelope?
  • Virolysis
Link to Answer Article
When coupled with antibodies, what mechanisms does complement aid in immune defence?
  • Blocking the virus receptor
  • Lysis of infected cells
  • Opsonisation of free particles or infected cells
Link to Answer Article
What are the main cytokines CD4+ T cells release to recruit macrophages?
  • IFN-γ
  • TNF
Link to Answer Article
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  • IFN-γ
  • TNF
Link to Answer Article