Butyrophenones

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Butyrophenones are sedative drugs, which have a potent anti-emetic effect.

Mechanism of Action

Butyrophenones antagonise dopamine transmission in the CNS.

Side Effects and Contraindications

Adverse effects in the CNS may occur, for example hallucinations and agitation have been reported in man. Vasodilation and hypotension also result from admministration.

Drugs in this Group

Azaperone

Azaperone is marketed under the trade name of Stresnil.