Campylobacter fetus subspecies venerealis

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  • Venereal infection of cattle
  • Infertility in female cattle
  • Found in glandular crypts of prepuce of bull with no clinical signs - carriers
  • Causes catarrhal inflammation in female genital tract
  • Endometritis prevents implantation until infection cleared and causes early embryonic death, occasionally sporadic abortion
  • May remain infertile for 3-5 months before immunity develops, which lasts 4-5 years
  • Effective immunity includes induction of IgA in the vagina and IgG in the uterus
  • Bacteria may persist in the vagina and be transmitted to bulls
  • Diagnosis:
    • Fluorescent antibody test on genital discharges from bull/cow
    • Vaginal mucus agglutination test
    • ELISA to IgA antibodies in vaginal mucus after an abortion
    • PCR for detection in semen
  • Treatment: dihydrostreptomycin intrauterine for cows and systemically or topically for bulls
  • Vaccination: bacterin in oil adjuvant