Difference between revisions of "Ascarid Impaction"

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#REDIRECT[[Ascarid Impaction - Horse]]
 
 
 
 
{| cellpadding="10" cellspacing="0" border="1"
 
| Also known as:
 
|'''Colic in foals<br>
 
'''Impaction<br>
 
'''Simple Obstruction<br>
 
'''Small Intestinal Simple Obstruction<br>
 
'''Small Intestinal Obstruction<br>
 
'''Small Intestinal Impaction'''
 
|}
 
 
 
 
 
 
 
 
==Signalment==
 
Foals younger than 6 months in poor condition, on a poor worming schedule and with a heavy parasite burden.<ref name="Bliks">Blikslager, A.T (2010) ''Obstructive Disorders of the Gastrointestinal Tract'' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), Chapter 15, ''Saunders''.</ref>  Adult horses demonstrate age-related immunity which starts to develop from around 6 months and is substantial by about 15 months depending on worm exposure.
 
 
 
==History==
 
 
 
Recent history (within the previous 24 hours) of being wormed with a product effective against ascarids.
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
==Aetiology==
 
 
 
Products that cause sudden death<ref name="Bliks">Blikslager, A.T (2010) ''Obstructive Disorders of the Gastrointestinal Tract'' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), Chapter 15, ''Saunders''.</ref> or paralysis<ref name="Merck">Merck & Co (2008) '''The Merck Veterinary Manual (Eighth Edition)''', ''Merial''.</ref> of ascarids, particularly [[Parascaris equorum|''Parascaris equorum'']] within the small intestine.  Adult ascarids are large and thus readily cause small intestinal impaction.<ref name="Bliks">Blikslager, A.T (2010) ''Obstructive Disorders of the Gastrointestinal Tract'' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), Chapter 15, ''Saunders''.</ref>  It has been suggested that disruption of the surface of the ascarid releases antigenic fluids that inhibit intestinal muscular activity, thereby increasing the likelihood of intestinal obstruction.<ref name="Merck">Merck & Co (2008) '''The Merck Veterinary Manual (Eighth Edition)''', ''Merial''.</ref>  Anthelmintics that are suspected to induce episodes of ascarid impaction include<ref name="Cribb">Cribb, N.C, Cote, N.M, Boure, L.P, Peregrine, A.S (2006) Acute small intestinal obstruction associated with ''Parascaris equorum'' infection in young horses: 25 cases (9185-2004).  ''N Z Vet J'', 54:338-343.  In: Blikslager, A.T (2010) ''Obstructive Disorders of the Gastrointestinal Tract'' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), Chapter 15, ''Saunders''.</ref>:
 
*Organophosphates
 
*[[Macrocyclic Lactones|Ivermectin]]
 
*Pyrantel pamoate
 
*Piperazine
 
 
 
 
 
==Clinical Signs==
 
 
 
*Acute onset mild to severe colic after administration of anthelmintic (onset varies with degree of obstruction<ref name="Cribb">Cribb, N.C, Cote, N.M, Boure, L.P, Peregrine, A.S (2006) Acute small intestinal obstruction associated with ''Parascaris equorum'' infection in young horses: 25 cases (9185-2004).  ''N Z Vet J'', 54:338-343.  In: Blikslager, A.T (2010) ''Obstructive Disorders of the Gastrointestinal Tract'' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), Chapter 15, ''Saunders''.</ref>)
 
*Signs compatible with [[Colic Diagnosis - Clinical Signs|small intestinal obtruction]]<ref name="Bliks">Blikslager, A.T (2010) ''Obstructive Disorders of the Gastrointestinal Tract'' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), Chapter 15, ''Saunders''.</ref>
 
**[[Colic Diagnosis - Naso-gastric Intubation|Nasogastric reflux]] (occasionally dead parasites are seen in reflux)
 
*The foal may be in poor body condition with a poor coat, pot-bellied appearance and stunted growth.<ref name="Merck">Merck & Co (2008) '''The Merck Veterinary Manual (Eighth Edition)''', ''Merial''.</ref>
 
 
 
 
 
==[[:Category:Colic_Diagnosis_in_the_Horse|Diagnosis]]==
 
 
 
*History
 
*[[Colic Diagnosis - Clinical Signs|Clinical signs]] referable to small intestinal obstruction
 
*Abdominal imaging (radiography and [[Colic Diagnosis - Abdominal Ultrasound|ultrasonography]]) may demonstrate multiple loops of distended small intestine, but imaging is not required if the clinical presentation indicates immediate surgery.<ref name="Bliks">Blikslager, A.T (2010) ''Obstructive Disorders of the Gastrointestinal Tract'' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), Chapter 15, ''Saunders''.</ref>
 
 
 
 
 
==Treatment<ref name="Bliks">Blikslager, A.T (2010) ''Obstructive Disorders of the Gastrointestinal Tract'' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), Chapter 15, ''Saunders''.</ref>==
 
 
 
*[[Colic, Medical Treatment|'''Medical treatment:''']] immediate treatment of hypovolaemic shock resulting from sequestration of fluid in small intestine
 
*'''Surgical treatment:''' enterotomy made over the intraluminal impaction and removal of ascarids
 
 
 
==Prognosis==
 
 
 
Fair in cases that are rapidly treated but poor in foals with evidence of hypovolaemia and septic shock.  Surgical cases also carry a poorer prognosis than cases which are resolved medically.<ref name="Merck">Merck & Co (2008) '''The Merck Veterinary Manual (Eighth Edition)''', ''Merial''.</ref>  In a recent study, long term survival of 25 affected horses was 33%.<ref name="Cribb">Cribb, N.C, Cote, N.M, Boure, L.P, Peregrine, A.S (2006) Acute small intestinal obstruction associated with ''Parascaris equorum'' infection in young horses: 25 cases (9185-2004).  ''N Z Vet J'', 54:338-343.  In: Blikslager, A.T (2010) ''Obstructive Disorders of the Gastrointestinal Tract'' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), Chapter 15, ''Saunders''.</ref>:  Failure to relieve the impaction may lead to intestinal rupture.<ref name="Merck">Merck & Co (2008) '''The Merck Veterinary Manual (Eighth Edition)''', ''Merial''.</ref>
 
 
 
 
 
 
 
 
 
 
 
 
 
==Prevention==
 
 
 
*Regular worming programme until at least 15 months of age that prevents a build-up of large ascarid burdens in the foal:
 
**Macrocyclic lactones (Ivermectin in Equimax® or Eqvalan® paste) 0.2mg/kg at 60 day intervals (NB: NOT the drug of choice because resistance is widespread)
 
**Tetrahydropyrimidines (Pyrantel embonate in Strongid-P® paste) 19mg/kg PO: for foals over 4 weeks of age up to eight months - dose every four weeks.  For horses over eight months of age routinely dose every 6 to 8 weeks, but during the summer and
 
autumn when at grass dose every 4 to 6 weeks.  Always dose three to four days before turning out after
 
in-wintering.
 
**Benzimidazoles (Fenbendazole in Panacur®) 10mg/kg PO at 56 day intervals
 
*For foals that have not been on a controlled programme or if a large burden is suspected:
 
**Fenbendazole at 5mg/kg PO (lower dose with only 50% efficacy against ''Parasacaris'')
 
**Followed one week later by a full dose of Fenbendazole at 10mg/kg PO
 
*Regular faecal worm egg counts should be conducted to monitor the effects of the anthelmintic schedule and the presence of resistance
 
*Clean pasture management including the regular removal of faeces
 
*The worming programme for adult horses should reflect the circumstances and efficiency of clean pasture management.  A strategic or targeted startegic dosing plan is recommended.
 
*Thorough cleaning of stables that have been occupied by foals or weanlings
 
*Bathe mare and clean udder before arrival at foaling premises to remove any ascarid eggs on the coat
 
 
 
==References==
 
 
 
Pasquini, C, Pasquini, S, Woods, P (2005) '''Guide to Equine Clinics Volume 1: Equine Medicine''' (Third edition), ''SUDZ Publishing''
 
 
 
<references/>
 
[[Category:Colic_in_Horses]]
 
[[Category:To_Do_-_Nina]]
 

Latest revision as of 14:53, 8 August 2010