Changes

===Renal azotaemia===

===Renal azotaemia===

This occurs following a direct insult to the kidney:

This occurs following a direct insult to the kidney from several possible causes including:

*'''Exogenous toxins''' including heavy metals, [[Aminoglycosides|aminoglycosides]], [[Tetracyclines|tetracyclines]], polymixin B, cisplatin, lilies in cats and grapes in dogs.

*'''Exogenous toxins''' including heavy metals, [[Aminoglycosides|aminoglycosides]], [[Tetracyclines|tetracyclines]], polymixin B, cisplatin, antifreeze (ethylene glycol), lilies in cats and grapes in dogs.

*'''Endogenous toxins''' including haemoglobin, myoglobin and calcium.

*'''Endogenous toxins''' including haemoglobin, myoglobin and calcium.

*Infection as in '''pyelonephritis''', '''interstitial nephritis''' (as caused by [[Leptospirosis - Cats and Dogs|''Leptospira spp.'']] or '''granulomatous nephritis''' (as caused by the dry form of [[Feline Infectious Peritonitis]]).

*Infections such as '''pyelonephritis''', '''interstitial nephritis''' (as caused by [[Leptospirosis - Cats and Dogs|''Leptospira spp.'']] or '''granulomatous nephritis''' (as caused by the dry form of [[Feline Infectious Peritonitis]]).

*'''Glomerulonephritis''' and '''[[Amyloidosis|amyloidosis]]'''.

*'''Glomerulonephritis''' and '''[[Amyloidosis|amyloidosis]]'''.

*'''Neoplasia''', including adenocarcinoma in dogs and lymphoma in cats.

*'''Neoplasia''', notably adenocarcinoma in dogs and lymphoma in cats.

 

===Post-renal azotaemia===  

===Post-renal azotaemia===  

This occurs following obstructions within the urinary tract:

This occurs following obstructions within the urinary tract: