5,582
edits
Changes
Jump to navigation
Jump to search
→Clinical Significance
==Clinical Significance==
==Clinical Significance==
The competence of enterohepatic circulation is usually assessed dynamically by performing a bile acid stimulation test; the patient is fasted for 12 hours and then fed a test meal and the serum bile acid concentration are measured before and two hours after the meal. The post-prandial measurement may be '''elevated''' in the following conditions:
The competence of enterohepatic circulation is usually assessed dynamically by performing a bile acid stimulation test; the patient is fasted for 12 hours and then fed a test meal and the serum bile acid concentration are measured before and two hours after the meal. The post-prandial measurement may be '''elevated''' in the following conditions:
[[Image:Maltese.jpg|thumb|right|150px|'''Maltese'''<p><small>( © sannse WikiMedia Commons)</small>]]
*'''Hepatobiliary disease'''; this is a non specific test for hepatobiliary disease.
*'''Hepatobiliary disease'''; this is a non specific test for hepatobiliary disease.
*'''Cholestasis''', including the mild cholestasis that occurs due to hepatic hydropic change in [[Canine Hyperadrenocorticism - Cushing's Disease|hyperadrenocorticism]] in dogs and [[Biliary Tract - Obstruction|extra-hepatic biliary obstruction]].
*'''Cholestasis''', including the mild cholestasis that occurs due to hepatic hydropic change in [[Canine Hyperadrenocorticism - Cushing's Disease|hyperadrenocorticism]] in dogs and [[Biliary Tract - Obstruction|extra-hepatic biliary obstruction]].
*[[Antibiotic Responsive Diarrhoea|'''Small intestinal bacterial overgrowth''']] due to deconjugation of bile acids by intestinal bacteria.
*[[Antibiotic Responsive Diarrhoea|'''Small intestinal bacterial overgrowth''']] due to deconjugation of bile acids by intestinal bacteria.
*Increased post-prandial bile acid concentration may be a normal finding in '''Maltese terriers'''.
*Increased post-prandial bile acid concentration may be a normal finding in '''Maltese terriers'''.
'''Deficiency''' of bile acids is extremely rare, even with severe hepatic insufficiency.
'''Deficiency''' of bile acids is extremely rare, even with severe hepatic insufficiency.
[[Category:Blood Biochemistry Changes]]
[[Category:Blood Biochemistry Changes]]