Changes

==Hyperbilirubinaemia==

==Hyperbilirubinaemia==

Bilirubin increases when the production of bilirubin exceeds the ability of the liver to recover unconjugated bilirubin from the bloodstream and process it, or when clearance of the conjugated form is altered by impaired hepatocyte processes or obstruction to the discharge of bilirubin into the intestines. Clinically, this means that hyperbilirubinaemia can be cased by heamolysis or choleostasis - the next step diagnostically is to establish if the inciting cause is prehepatic, hepatic or posthepatic.

Bilirubin increases when the production of bilirubin exceeds the ability of the liver to recover unconjugated bilirubin from the bloodstream and process it, or when clearance of the conjugated form is altered by impaired hepatocyte processes or obstruction to the discharge of bilirubin into the intestines. Clinically, this means that hyperbilirubinaemia can be cased by heamolysis or choleostasis - the next step diagnostically is to establish if the inciting cause is [[Icterus#Causes_of_Icterus|prehepatic]], [[Icterus#Causes_of_Icterus|hepatic]] or [[Icterus#Causes_of_Icterus|posthepatic]].

==Bilirubin in horses==

==Bilirubin in horses==