Difference between revisions of "Bone & Cartilage Development - Anatomy & Physiology"
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(New page: <big><center>'''BACK TO DEVELOPMENTAL BIOLOGY</center></big>) |
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<big><center>[[Developmental Biology - Anatomy & Physiology|'''BACK TO DEVELOPMENTAL BIOLOGY]]</center></big> | <big><center>[[Developmental Biology - Anatomy & Physiology|'''BACK TO DEVELOPMENTAL BIOLOGY]]</center></big> | ||
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| + | ==Introduction== | ||
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| + | Osteogenesis is the formation of bone. Bone forms from one of three lineages; the skull forms from neural cest; the limb skeleton forms from lateral plate mesoderm; and the axial skeleton forms from paraxial mesoderm (sclerotome). There are two methods of osteogenesis. Both involve the transformation of pre - existing mesenchymal tissue into bone. | ||
| + | #'''Intramembranous Ossification''' - direct conversion of mesenchymal tissue into bone. Occurs in production of the skull. | ||
| + | #'''Endochondrial Ossification''' - mesechymal tissue first differentiates into cartilage, then into bone. This occurs in the production of limb and axial skeleton. | ||
| + | #*Limb cartilage is produced in a proximal to distal direction as a continuous structure. It becomes punctuated with joints later, and then converted to bone. | ||
Revision as of 09:30, 31 August 2008
Introduction
Osteogenesis is the formation of bone. Bone forms from one of three lineages; the skull forms from neural cest; the limb skeleton forms from lateral plate mesoderm; and the axial skeleton forms from paraxial mesoderm (sclerotome). There are two methods of osteogenesis. Both involve the transformation of pre - existing mesenchymal tissue into bone.
- Intramembranous Ossification - direct conversion of mesenchymal tissue into bone. Occurs in production of the skull.
- Endochondrial Ossification - mesechymal tissue first differentiates into cartilage, then into bone. This occurs in the production of limb and axial skeleton.
- Limb cartilage is produced in a proximal to distal direction as a continuous structure. It becomes punctuated with joints later, and then converted to bone.