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==Introduction==
 
==Introduction==
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The '''periosteum''' lines the outer surface of the diaphysis of the bone. It has a cellular inner layer, consisting of osteoblasts, and a fibrous outer layer. The '''endosteum''' lines the inner surface of the diaphysis of the bone. It contains osteoblasts ''and'' osteoclasts. Bone growth occurs by a shift in the equilibrium between osteoblasts and osteoclasts. Osteoblasts on the outside in the periosteum add bone to increase the bone's diameter. Osteoclasts on the inside in the endosteum remove this bone to maintain the bone diameter. When osteoclasts start removing less bone, or osteoblasts start adding more bone, the girth increases.
 
The '''periosteum''' lines the outer surface of the diaphysis of the bone. It has a cellular inner layer, consisting of osteoblasts, and a fibrous outer layer. The '''endosteum''' lines the inner surface of the diaphysis of the bone. It contains osteoblasts ''and'' osteoclasts. Bone growth occurs by a shift in the equilibrium between osteoblasts and osteoclasts. Osteoblasts on the outside in the periosteum add bone to increase the bone's diameter. Osteoclasts on the inside in the endosteum remove this bone to maintain the bone diameter. When osteoclasts start removing less bone, or osteoblasts start adding more bone, the girth increases.
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==Joint Formation==
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Joints begin to form as the mesenchyme is condensing. Joint-forming cells develop different characteristics to cartilage precursors; they are flat and densely packed. The region where these joint-forming cells exist is called the "interzone". There are three layers in the interzone, a middle layer of low density with regions of high density either side. The high density regions form cartilage. The middle layer is eliminated by cell death, forming the joint space.
         
[[Category:Developmental Biology]][[Category:Bone and Cartilage - Anatomy & Physiology]]
 
[[Category:Developmental Biology]][[Category:Bone and Cartilage - Anatomy & Physiology]]
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