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Bone & Cartilage Development - Anatomy & Physiology (view source)
Revision as of 16:50, 30 December 2010
, 16:50, 30 December 2010→Introduction
==Introduction==
==Introduction==
Osteogenesis is the formation of [[Bones and Cartilage - Anatomy & Physiology#Types of Bone|bone]]. Bone forms from one of three lineages; the skull forms from [[Neurogenesis - Anatomy & Physiology#Neural Crest|neural cest]]; the limb skeleton forms from lateral plate mesoderm; and the axial skeleton forms from paraxial mesoderm (sclerotome). There are two methods of osteogenesis. Both involve the transformation of pre - existing mesenchymal tissue into bone.
'''Osteogenesis''' is the formation of [[Bones and Cartilage - Anatomy & Physiology#Types of Bone|bone]]. Bone forms from one of three lineages; the skull forms from the [[Neurogenesis - Anatomy & Physiology#Neural Crest|neural cest]]; the limb skeleton forms from the lateral plate mesoderm; and the axial skeleton forms from the paraxial mesoderm (sclerotome). There are two methods of osteogenesis. Both involve the transformation of the pre - existing mesenchymal tissue into bone.
1. '''Intramembranous Ossification''' - The direct conversion of mesenchymal tissue into bone. Occurs in production of the skull.
2.'''Endochondrial Ossification''' - The mesechymal tissue first differentiates into [[Bones and Cartilage - Anatomy & Physiology#Structure and Function of Cartilage|cartilage]], then into bone. This occurs in the production of the limb and axial skeleton. Limb cartilage is produced in a proximal to distal direction as a continuous structure. It becomes punctuated with [[Developmental Biology Overview - Anatomy & Physiology#Joints|joints]] later, and then converted to bone.
==Endochondrial Ossification==
==Endochondrial Ossification==