Changes

==Viral Characteristics==

==Viral Characteristics==

CAV-1 is a non-enveloped virus with an icosohedral nucleocapsid that containes a single, lenear molecule of double-stranded DNA.

The genetic information of CAV-1, like other Adenoviridae, is conveyed by a single, linear molecule of double-stranded DNA. This is contained within a non-enveloped icosohedral nucleocapsid, which comprises capsomeres (called hexons) and twelve vertex capsomeres  (called pentons). A fibre antigen which is used to attach to host cell receptors and initiate replication, protrudes from each of the twelve pentons. This fibre antige is a feature specific to the Adenoviridae.  

 

The  capsid consists of capsomeres (called hexons) and 12 vertex capsomeres  (called pentons). These are the only viruses with a fiber (the fiber  antigen) protruding from each of the 12 pentons (see Fig. 13-1).

The fiber is the structure of attachment to host cells and is also a type specific hemagglutinin.

The fiber is the structure of attachment to host cells and is also a type specific hemagglutinin.

The hexon of mammalian adenoviruses contains a cross-reacting group antigen.

The hexon of mammalian adenoviruses contains a cross-reacting group antigen.