Changes

*Aerosol infection

*Aerosol infection

*Infects alveolar [[Macrophages|macrophages]] or [[Oropharynx - Pathology|oropharynx]]

*Infects alveolar [[Macrophages|macrophages]] or [[Oropharynx - Pathology|oropharynx]]

*Multiplies in the bronchial and other lymph nodes, infects [[Monocytes - WikiBlood|monocytes]] and dendritic cells

*Multiplies in the bronchial and other lymph nodes, infects [[Monocytes|monocytes]] and dendritic cells

*Viraemia

*Viraemia

*Spreads via [[Monocytes - WikiBlood|monocytes]] to a variety of epithelium depending upon the strain of virus  

*Spreads via [[Monocytes|monocytes]] to a variety of epithelium depending upon the strain of virus  

*[[Respiratory Viral Infections - Pathology#Canine distemper|Respiratory]] and alimentary tracts, skin and later (1-5 wk. post infection) to the brain

*[[Respiratory Viral Infections - Pathology#Canine distemper|Respiratory]] and alimentary tracts, skin and later (1-5 wk. post infection) to the brain

*'''Clinical signs''':

*'''Clinical signs''':