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| − | *Anaerobic, intestinal spirochaetes, found in normal and diseased pigs
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| − | *Enterophogens of pigs
| + | |pagetitle =Brachyspira and Serpulina |
| − | *''B. hyodysenteriae, B. pilosicoli, B. innocens, Serpulina intermedia'' and ''S. murdochii'' occur in pigs
| + | |pagebody =The ''Brachyspira'' and ''serpulina'' species are anaerobic, intestinal ''[[spirochaetes]]'', found in normal and diseased pigs. |
| − | *Carrier pigs shed ''B. hyodysenteriae'' for up to 3 months, acting as a source of infection for healthy pigs
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| − | *Demonstrated in stained faecal smears or silver-stained histopathology sections
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| − | *Cultured anaerobically on selective blood agar
| + | <categorytree mode=pages>Brachyspira and Serpulina</categorytree> |
| − | *Spirochaetes differentiated by pattern of haemolysis on blood agar as well as molecular techniques
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| − | *Pathogenesis
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| − | **Motility in mucous allows colonisation of pig intestine
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| − | **Haemolytic and cytotoxic activiity important for virulence
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| − | **Attachment of ''B. pilosicoli'' to epithelial cells of colonic mucosa disrupts their function and leads to their shedding and oedema
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| − | *Clinical infections
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| − | [[Brachyspira hyodysenteriae]]
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| − | [[Brachyspira pilosicoli]] | + | [[Category:Spirochaetaceae]] |
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| − | **''B. pilosicoli'' causes porcine intestinal spirochaetosis
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| − | **Infection is acquired via contaminated faeces
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| − | **Disease spreads slowly through the herd
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| − | **Dogs, rats, mice and flies may act as transport hosts
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| − | *Clinical signs
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| − | **''B. pilosicoli'' causes less severe signs than [[Brachyspira hyodysenteriae|swine dysentry]]; reduced feed conversion rates occur
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| − | *Diagnosis
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| − | **History, clinical signs and gross pathology
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| − | **Anaerobic culture on blood agar with added antibiotics for at least 3 days
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| − | **Immunofluorescence, DNA probes and biochemical tests
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| − | **Serology using ELISA can be used on a herd basis
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| − | **PCR
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