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====Dog====
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====Pig====
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====[[Gastric Ulceration - Pig]]====
[[Gastric Ulceration - all species]]
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* Gastic ulceration is quite common in the pig- May be seen in 50-60% of pigs arriving at slaughterhouses.
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* Has serious economic consequences.
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*'''Clinical'''
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** Occasionally a well-grown pig will drop dead.
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*** Deep ulcers have eroded into a blood vessel, causing massive haemorrhage into the [[Forestomach - Anatomy & Physiology|stomach]] from and producing death very rapidly.
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** If long standing ulcers do not result in death, they do produce pain and discomfort.
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*** Give low growth rate and poor feed conversion.
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*'''Pathogenesis'''
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** Gastric ulceration is associated with modern pig rearing, but the exact cause is unknown.
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** Causes are associated with gastric hyperacidity, and gastric ulceration is probably a multifactorial disease.
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** The following are suggested as possible causes:
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*** Infection, e.g. ''Candida albicans'', ''Streptococci'', ''Staphylococci'' and mixes of these.
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*** Copper toxicity- this is probably more significant.
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**** Pigs are fed copper as growth promoter; 50 ppm is know to be toxic, and animals are often fed 250 ppm.
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*** Vitamin E / Selenium deficiency.
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*** Feeding on concrete floors.
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**** Sand is licked up whe pigs eat.
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*** Feeding finely milled cereal.
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*** Stress
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*** Possibly genetic factors.
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*'''Pathology'''
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** Most commonly affects pars oesophagea (squamous or non-glandular portion).
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** Starts with hyperkeratosis in the stratum corneum
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*** Appears rough and thickened
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*** May stop at this stage.
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** In approximately 30% of animals, the lesion starts to erode and quite deep ulcers may develop.
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** In a significant small number ,very deep ulcers develop and may affect virtually all of pars oesophagea.
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** Histologically, ulcers are large and flask-shaped ulcer with fibrin, necrosis, erosion and fibrosis at base.
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[[Category:Stomach_and_Abomasum_-_Inflammatory_Pathology]]
 
[[Category:Stomach_and_Abomasum_-_Inflammatory_Pathology]]
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