Changes

*bacteria can enter the [[Liver - Anatomy & Physiology|liver]] through a variety of routes

*bacteria can enter the [[Liver - Anatomy & Physiology|liver]] through a variety of routes

**direct implantation

**direct implantation

***eg foreign body penetration from [[The Reticulum - Anatomy & Physiology|reticulum]]

***eg foreign body penetration from [[Reticulum - Anatomy & Physiology|reticulum]]

**direct extension from disease in adjacent tissues of supportive [[Peritonitis - Pathology|peritonitis]]

**direct extension from disease in adjacent tissues of supportive [[Peritonitis|peritonitis]]

**haematogenously

**haematogenously

***via the umbilical vein from an infected umbilicus

***via the umbilical vein from an infected umbilicus

***via the portal vein in the [[Alimentary - Anatomy & Physiology|alimentary tract]]

***via the portal vein in the [[Alimentary System Overview - Anatomy & Physiology|alimentary tract]]

***via the hepatic artery in bacteraemias and septicaemias

***via the hepatic artery in bacteraemias and septicaemias

***via the bile ducts

***via the bile ducts

*the [[Liver - Anatomy & Physiology|liver]] may show microscopic evidence of involvement in a large variety of systemic infections

*the [[Liver - Anatomy & Physiology|liver]] may show microscopic evidence of involvement in a large variety of systemic infections

*these can be accompanied by jaundice

*these can be accompanied by jaundice

*the changes in the [[Liver - Anatomy & Physiology|liver]] are diffuse with many small areas of necrosis surrounded by [[Neutrophils|neutrophils]] and [[Lymphocytes - WikiBlood|lymphocytes]]

*the changes in the [[Liver - Anatomy & Physiology|liver]] are diffuse with many small areas of necrosis surrounded by [[Neutrophils|neutrophils]] and [[Lymphocytes - Introduction|lymphocytes]]

**eg Salmonellosis or Listeriosis

**eg Salmonellosis or Listeriosis

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[[Category:Liver_-_Inflammatory_Pathology]]

[[Category:Liver_-_Inflammatory_Pathology]]