Changes

'''Fourth Generation Cephalosporins''' - Cefquinome

'''Fourth Generation Cephalosporins''' - Cefquinome

* Very broad spectrum, only the very hardiest of gram negatives aren't susceptible. It is still active againts ''Pseudomonas''.

* Very broad spectrum, only the very hardiest of gram negatives aren't susceptible. It is still active against ''Pseudomonas''.

==Pharmacokinetic Considerations==

==Pharmacokinetic Considerations==

* Very high doses has been known to result in nephrotoxicity.

* Very high doses has been known to result in nephrotoxicity.

* They can result in bleeding problems because of interference with the formation of vitamin K in the gut (esp Moxalactam).

* They can result in bleeding problems because of interference with the formation of vitamin K in the gut (esp Moxalactam).