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* '''Collagen fibre bundles''': helical strands of amino acids bound together to form fibrils
 
* '''Collagen fibre bundles''': helical strands of amino acids bound together to form fibrils
 
* '''Proteoglycan Matrix''': protein core with '''glycosaminoglycan''' branches '''(GAGs)'''.  GAGs determine the degree of collagen fibre aggregation.  An increased GAG content reduces collagen aggregation and vice versa.
 
* '''Proteoglycan Matrix''': protein core with '''glycosaminoglycan''' branches '''(GAGs)'''.  GAGs determine the degree of collagen fibre aggregation.  An increased GAG content reduces collagen aggregation and vice versa.
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Cervical softening involves two changes in the intracellular matrix:
 
Cervical softening involves two changes in the intracellular matrix:
*
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* Reduction of collagen fibres
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* Increase in GAGs to decrease aggregation of the remaining collagen fibres.
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