Changes

==Description==

==Description==

'''Lymphocytic cholangitis''' is a slowly progressive chronic disease characterised by infiltration of the portal areas of the liver with inflammatory cells, mostly [[Lymphocytes - WikiBlood|lymphocytes]] and [[B cell differentiation - WikiBlood#Plasma cells|plasma cells]].  Bile duct hypertrophy and [[Liver General Pathology - Pathology#Fibrosis - Repair|fibrosis]] are present.  However, lymphocytic cholangitis does not progress to biliary [[Liver General Pathology - Pathology#Cirrhosis|cirrhosis]].  An immune-mediated aetiology has been postulated but this has not been substantiated to date.  It is rarely associated with [[Pancreatitis - WikiClinical|pancreatitis]], compared to [[Neutrophilic Cholangitis]]

'''Lymphocytic cholangitis''' is a slowly progressive chronic disease characterised by infiltration of the portal areas of the liver with inflammatory cells, mostly [[Lymphocytes - WikiBlood|lymphocytes]] and [[B cell differentiation - WikiBlood#Plasma cells|plasma cells]].  Bile duct hypertrophy and [[Liver Fibrosis|fibrosis]] are present.  However, lymphocytic cholangitis does not progress to biliary [[Cirrhosis|cirrhosis]].  An immune-mediated aetiology has been postulated but this has not been substantiated to date.  It is rarely associated with [[Pancreatitis - WikiClinical|pancreatitis]], compared to [[Neutrophilic Cholangitis]]

**weight loss

**weight loss

**intermittent [[Stomach and Abomasum Consequences of Gastric Disease - Pathology|vomiting]] and [[Diarrhoea|diarrhoea]]

**intermittent [[Stomach and Abomasum Consequences of Gastric Disease - Pathology|vomiting]] and [[Diarrhoea|diarrhoea]]

**[[Liver General Pathology - Pathology#Jaundice (Icterus)|jaundice]]

**[[Icterus|jaundice]]

**lymphadenomegaly

**lymphadenomegaly

*Severe illness and pyrexia is less likely compared to [[Neutrophilic Cholangitis]].   

*Severe illness and pyrexia is less likely compared to [[Neutrophilic Cholangitis]].